Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30886483 | 0.81 | PARP1 (0.53) | PARP1PARP2PARP3KDM4EALDH1A1 | |
| SCHEMBL29683769 | 0.78 | ALDH1A1 (0.46) | MEN1MAPTKMT2ASMN1; SMN2KDR | |
| SCHEMBL5116 | 0.78 | ALDH1A1 (0.46) | MEN1MAPTKMT2ASMN1; SMN2KDR | |
| SCHEMBL719667 | 0.75 | ALDH1A1 (0.44) | MEN1MAPTKMT2ASMN1; SMN2KDR | |
| SCHEMBL19331488 | 0.75 | ALDH1A1 (0.44) | MEN1POLBMAPTMAPK1HTT | |
| SCHEMBL27419112 | 0.75 | PARP1 (0.53) | PARP1PARP2PARP3KDM4EALDH1A1 | |
| SCHEMBL458716 | 0.75 | KDR (0.54) | MEN1POLBMAPTMAPK1HTT | |
| SCHEMBL27544144 | 0.73 | PARP1 (0.51) | PARP1PARP2PARP3KDM4EALDH1A1 | |
| SCHEMBL1881135 | 0.73 | ALDH1A1 (0.45) | MEN1MAPTKMT2ASMN1; SMN2KDR | |
| SCHEMBL5043535 | 0.72 | ALDH1A1 (0.44) | MEN1MAPTKMT2ASMN1; SMN2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |