Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.46 |
| ▸ | PIM1 | P11309 | 4/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210719 | 0.83 | ALDH1A1 (0.56) | ERN1PIM3PIM1PRKDCALDH1A1 | |
| SCHEMBL29954105 | 0.81 | ALDH1A1 (0.44) | ERN1PIM3PIM1PRKDCALDH1A1 | |
| SCHEMBL29957614 | 0.81 | ERN1 (0.51) | ERN1PIM3PIM1PRKDCALDH1A1 | |
| SCHEMBL674053 | 0.79 | TRIM24 (0.56) | ERN1PIM3PIM1ALDH1A1KDM4E | |
| SCHEMBL18426484 | 0.78 | PIM3 (0.51) | ERN1PIM3PIM1ALDH1A1KDM4E | |
| SCHEMBL29955189 | 0.77 | PIM3 (0.50) | ERN1PIM3PIM1ALDH1A1KDM4E | |
| SCHEMBL29954576 | 0.76 | ALDH1A1 (0.56) | ERN1PIM3PIM1PRKDCALDH1A1 | |
| SCHEMBL29953212 | 0.76 | PIM3 (0.49) | ERN1PIM3PIM1ALDH1A1KDM4E | |
| SCHEMBL1612856 | 0.75 | ERN1 (0.51) | ERN1PIM3PIM1PRKDCALDH1A1 | |
| SCHEMBL29952579 | 0.75 | PIM3 (0.48) | ERN1PIM3PIM1PRKDCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |