Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955644 | 0.79 | ERN1 (0.59) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL11504978 | 0.79 | ERN1 (0.59) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL29956480 | 0.78 | KDM4E (0.58) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL1071836 | 0.78 | KDM4E (0.58) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL10547808 | 0.78 | ERN1 (1.00) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL6571673 | 0.78 | KDM4E (0.52) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL6571662 | 0.78 | KDM4E (0.52) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL3155534 | 0.78 | KDM4E (0.62) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL1161054 | 0.77 | KDM4E (0.56) | ERN1KMT2AMEN1KDM4EHSP90AA1 | |
| SCHEMBL3409403 | 0.77 | KDM4E (0.56) | ERN1KMT2AMEN1KDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |