SCHEMBL29951463

SCHEMBL29951463

N[C@@H](CC(=O)O)C1CCC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
DPP4 P27487 3/20 0.38
EPHX1 P07099 2/20 0.37
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
GABRR1 P24046 2/20 0.34
LMNA P02545 1/20 0.34
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 1/20 0.34
ALOX5 P09917 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FFAR1 O14842 1/20 0.33
ANPEP P15144 2/20 0.33
REN P00797 1/20 0.33
ACE P12821 1/20 0.33
ENPEP Q07075 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14677519 1.00 ALDH1A1 (0.52) ALDH1A1DPP4EPHX1SLC1A3SLC1A2
SCHEMBL29955709 1.00 ALDH1A1 (0.52) ALDH1A1DPP4EPHX1SLC1A3SLC1A2
SCHEMBL4635158 0.95 ALDH1A1 (0.57) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL7250582 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL7250579 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL7250575 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL1255799 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL5362998 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL5416686 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1
SCHEMBL6694693 0.93 ALDH1A1 (0.60) ALDH1A1DPP4EPHX1LMNAGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed