SCHEMBL29951499

SCHEMBL29951499

Cc1cc(N(CC(N)=O)CC(N)=O)ccc1C=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
S100B P04271 1/20 0.37
TSHR P16473 1/20 0.35
MAPT P10636 7/20 0.35
KDM4E B2RXH2 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
HTT P42858 2/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
PKM P14618 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GAA P10253 1/20 0.34
SRC P12931 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2562483 0.89 SLC16A3 (0.39) ALDH1A1L3MBTL1S100BTSHRMAPT
SCHEMBL29956977 0.88 SLC16A3 (0.40) ALDH1A1L3MBTL1S100BMAPTKDM4E
SCHEMBL2561083 0.86 ALDH1A1 (0.34) ALDH1A1L3MBTL1TSHRMAPTKDM4E
SCHEMBL2563042 0.82 IGLV6-57 (0.36) ALDH1A1L3MBTL1TSHRNPC1RAB9A
SCHEMBL29955001 0.79 S1PR1 (0.39) ALDH1A1L3MBTL1SMN1; SMN2MEN1HPGD
SCHEMBL10671772 0.79 ALDH1A1 (0.49) ALDH1A1L3MBTL1S100BMAPTKDM4E
SCHEMBL2845181 0.78 ALDH1A1 (0.63) ALDH1A1L3MBTL1S100BTSHRMAPT
SCHEMBL8024385 0.78 MAPT (0.46) ALDH1A1L3MBTL1S100BTSHRMAPT
SCHEMBL29957410 0.77 ALDH1A1 (0.47) ALDH1A1L3MBTL1S100BMAPTKDM4E
SCHEMBL29953743 0.76 ALDH1A1 (0.46) ALDH1A1L3MBTL1S100BTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed