Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329808 | 0.88 | BRD4 (0.37) | KDM4EMAPTMEN1KMT2ABRD4 | |
| SCHEMBL29953299 | 0.88 | TNKS2 (0.37) | KDM4EPTGS2ALDH1A1LMNA | |
| SCHEMBL29957064 | 0.85 | KDM4E (0.34) | KDM4EMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL15331202 | 0.85 | TYR (0.39) | KDM4EMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL29952044 | 0.83 | MAPT (0.49) | ADORA2AADORA2BMAPTMEN1KMT2A | |
| SCHEMBL29953116 | 0.82 | KDM4E (0.37) | KDM4EMAPTMEN1KMT2AERN1 | |
| SCHEMBL15332255 | 0.81 | KDM4E (0.39) | KDM4EMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL2553502 | 0.81 | ERN1 (0.39) | KDM4EPTGS2ERN1 | |
| SCHEMBL2555181 | 0.78 | KDM4E (0.35) | KDM4EADORA2AADORA2BCYP2A6MAPT | |
| SCHEMBL15330850 | 0.78 | TRIM24 (0.43) | KDM4EMAPTKMT2APTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |