Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951634 | 0.85 | KDM4E (0.38) | KDM4ECYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL29953299 | 0.82 | TNKS2 (0.37) | KDM4EALDH1A1LMNA | |
| SCHEMBL15329808 | 0.82 | BRD4 (0.37) | KDM4ECYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL15330854 | 0.81 | TRIM24 (0.39) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2554353 | 0.81 | ERN1 (0.34) | KDM4EMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL15331202 | 0.80 | TYR (0.39) | KDM4ECYP1A2CYP2C19CYP3A4MET | |
| SCHEMBL29954926 | 0.79 | GCGR (0.34) | CYP1A2CYP2C19CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL29952044 | 0.78 | MAPT (0.49) | CYP3A4MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29958306 | 0.77 | ERN1 (0.38) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29951627 | 0.77 | MAPT (0.38) | CYP1A2CYP2C19CYP3A4METMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |