Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.33 |
| ▸ | PDE4A | P27815 | 8/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.33 |
| ▸ | CBLB | Q13191 | 4/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13033012 | 0.80 | PDE10A (0.50) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL29841731 | 0.76 | CYP1A2 (0.42) | — | |
| SCHEMBL27271991 | 0.76 | PDE4D (0.36) | PDE4D | |
| SCHEMBL18069346 | 0.76 | PDE10A (0.41) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL24500132 | 0.72 | PDE10A (0.43) | PDE10ALDHACHRM3PDE4APDE4B | |
| SCHEMBL21211777 | 0.72 | PDE10A (0.43) | PDE10ALDHACHRM3PDE4APDE4B | |
| SCHEMBL29952455 | 0.71 | ALDH1A1 (0.36) | PDE4A | |
| SCHEMBL28979288 | 0.71 | HTT (0.43) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL3089372 | 0.71 | ALDH1A1 (0.36) | PDE4A | |
| SCHEMBL23219923 | 0.71 | PDE10A (0.42) | PDE10ALDHACHRM3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |