Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14875768 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDHTTTTRMEN1 | |
| SCHEMBL751221 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTTTRMEN1 | |
| SCHEMBL3788331 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HPGDHTTTTRMEN1 | |
| SCHEMBL29958288 | 0.82 | HSP90AA1 (0.45) | ALDH1A1HPGDTTRMAPTLMNA | |
| SCHEMBL15465164 | 0.79 | AR (0.45) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL1043126 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL29954641 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TTRMEN1KMT2AMAPT | |
| SCHEMBL787718 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TTRMEN1KMT2AMAPT | |
| SCHEMBL22575311 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL4363897 | 0.77 | ALDH1A1 (0.66) | ALDH1A1HPGDHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |