Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724974 | 0.74 | GAA (0.49) | LRRK2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL6825991 | 0.74 | CCNA2 (0.38) | LRRK2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL4605475 | 0.73 | ACACB (0.35) | — | |
| SCHEMBL9591 | 0.72 | QPCT (0.37) | — | |
| SCHEMBL29953563 | 0.69 | MEN1 (0.41) | HSP90AA1HSP90B1 | |
| SCHEMBL11059945 | 0.68 | HTT (0.35) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL25311766 | 0.68 | RIPK1 (0.33) | — | |
| SCHEMBL30507918 | 0.68 | RIPK1 (0.33) | — | |
| SCHEMBL30507920 | 0.68 | RIPK1 (0.33) | — | |
| SCHEMBL23245068 | 0.68 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |