Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393863 | 1.00 | KDM4E (0.37) | KDM4EMAPTTDP1GAAL3MBTL1 | |
| SCHEMBL389682 | 0.84 | GAA (0.40) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL391293 | 0.80 | LMNA (0.43) | LMNACYP11B1CYP11B2MAPK8MAPK9 | |
| SCHEMBL13678427 | 0.77 | KDM4E (0.40) | KDM4EMAPTTDP1GAAL3MBTL1 | |
| SCHEMBL16734396 | 0.77 | SLC13A5 (0.33) | MAPTGAAMAPK1 | |
| SCHEMBL31032949 | 0.77 | HPGD (0.33) | MAPTGAAHSD17B10 | |
| SCHEMBL20738207 | 0.76 | MAPT (0.40) | KDM4EMAPTTDP1GAAL3MBTL1 | |
| SCHEMBL14659133 | 0.76 | SYK (0.31) | L3MBTL1 | |
| SCHEMBL17776991 | 0.76 | KDM4E (0.40) | KDM4EMAPTTDP1GAAL3MBTL1 | |
| SCHEMBL13514630 | 0.76 | KDM4E (0.40) | KDM4EMAPTTDP1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |