Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955416 | 0.78 | CCR1 (0.48) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL7675195 | 0.78 | CCR1 (0.48) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL28114355 | 0.78 | CCR1 (0.48) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL14280476 | 0.77 | CCR1 (0.40) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL29956349 | 0.77 | CCR1 (0.47) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL28943229 | 0.77 | CCR1 (0.47) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL18052210 | 0.77 | ERN1 (0.48) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL16237972 | 0.75 | CCR1 (0.45) | ERN1CCR1CCR5CCR8KDM4E | |
| SCHEMBL2894661 | 0.75 | CCR1 (0.45) | ERN1CCR1CCR5CCR8MEN1 | |
| SCHEMBL31130636 | 0.75 | CCR1 (0.45) | ERN1CCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |