Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956360 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2RAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL21032673 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL29950950 | 0.76 | NPC1 (0.49) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL568038 | 0.75 | — | — | |
| SCHEMBL4551794 | 0.75 | HTT (0.38) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL16347183 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1L3MBTL1KDM4E | |
| SCHEMBL31332862 | 0.73 | HTT (0.37) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL25423635 | 0.72 | — | — | |
| SCHEMBL13440864 | 0.72 | — | — | |
| SCHEMBL2513813 | 0.72 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |