Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605189 | 1.00 | NR1H2 (0.38) | NR1H2CA12CA9MEN1KMT2A | |
| SCHEMBL29955454 | 0.90 | NR1H2 (0.39) | NR1H2CA12CA9MEN1KMT2A | |
| SCHEMBL2930214 | 0.90 | NR1H2 (0.39) | NR1H2CA12CA9MEN1KMT2A | |
| SCHEMBL29955923 | 0.85 | NR1H2 (0.43) | NR1H2CA12CA9CCR9NR1H3 | |
| SCHEMBL594086 | 0.85 | NR1H2 (0.43) | NR1H2CA12CA9CCR9NR1H3 | |
| SCHEMBL15727386 | 0.84 | USP30 (0.43) | NR1H2CA12CA9CCR9NR1H3 | |
| SCHEMBL31601069 | 0.84 | NR1H2 (0.38) | NR1H2CA12CA9NR1H3 | |
| SCHEMBL513618 | 0.84 | NR1H2 (0.38) | NR1H2CA12CA9NR1H3 | |
| SCHEMBL29954465 | 0.84 | AURKA (0.35) | NR1H2CA12CA9MEN1KMT2A | |
| SCHEMBL513258 | 0.83 | NR1H2 (0.45) | NR1H2CA12CA9CCR9NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |