Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 11/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21812307 | 0.91 | AURKA (0.34) | AURKACDK2NR1H2CA12CA9 | |
| SCHEMBL1551648 | 0.89 | SUV39H2 (0.37) | AURKACDK2NR1H2 | |
| SCHEMBL20874957 | 0.86 | ACLY (0.36) | AURKACDK2NR1H2CA12CA9 | |
| SCHEMBL25787027 | 0.84 | NR1H2 (0.35) | NR1H2CA12CA9NR1H3GABRG2 | |
| SCHEMBL29951847 | 0.84 | NR1H2 (0.38) | NR1H2CA12CA9NR1H3MEN1 | |
| SCHEMBL2930214 | 0.84 | NR1H2 (0.39) | NR1H2CA12CA9NR1H3MEN1 | |
| SCHEMBL1605189 | 0.84 | NR1H2 (0.38) | NR1H2CA12CA9NR1H3MEN1 | |
| SCHEMBL29955454 | 0.84 | NR1H2 (0.39) | NR1H2CA12CA9NR1H3MEN1 | |
| SCHEMBL17422746 | 0.83 | NR1H2 (0.34) | NR1H2CA12CA9NR1H3GABRG2 | |
| SCHEMBL24076617 | 0.82 | STING1 (0.36) | NR1H2CA12CA9NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |