Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331366 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2PTGS2MAPK14GCGRLMNA | |
| SCHEMBL15332557 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL15332084 | 0.87 | CNR1 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL29955457 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPK14LMNAMAPTALDH1A1 | |
| SCHEMBL15329681 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK14LMNAMAPTALDH1A1 | |
| SCHEMBL29954645 | 0.82 | TNKS2 (0.40) | SMN1; SMN2PTGS2MAPK14GCGRMAPT | |
| SCHEMBL15331031 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL15333338 | 0.81 | CYP19A1 (0.43) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL15330463 | 0.79 | MEN1 (0.48) | SMN1; SMN2MAPK14GCGRLMNAMAPT | |
| SCHEMBL15329514 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK14GCGRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |