Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | APOL1 | O14791 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951123 | 0.90 | MAPT (0.42) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL15332815 | 0.89 | APOL1 (0.46) | TNKS2ALDH1A1APOL1 | |
| SCHEMBL15332833 | 0.89 | MAPT (0.41) | TNKS2MAPTMGAMGAASI | |
| SCHEMBL15329748 | 0.86 | ERN1 (0.40) | TNKS2MAPTMGAMGAASI | |
| SCHEMBL15330604 | 0.86 | MAPT (0.40) | MAPTABCB1SMN1; SMN2FFAR4PTGS2 | |
| SCHEMBL29951636 | 0.85 | TNKS2 (0.44) | TNKS2MAPTMGAMGAASI | |
| SCHEMBL29951627 | 0.84 | MAPT (0.38) | MAPTABCB1SMN1; SMN2ERN1 | |
| SCHEMBL2557465 | 0.84 | MAPT (0.38) | MAPTABCB1SMN1; SMN2ERN1 | |
| SCHEMBL2562653 | 0.83 | MEN1 (0.41) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL15332296 | 0.83 | MAPT (0.37) | MAPTMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |