Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952388 | 0.82 | PSMD14 (0.42) | PLGPLAUPSMD14ERN1ALDH1A1 | |
| SCHEMBL29956035 | 0.79 | CCNT1 (0.38) | PLGPLAUCCNT1CDK9HASPIN | |
| SCHEMBL2671391 | 0.78 | HCAR2 (0.44) | PSMD14HCAR2MGAMP4HA1P4HTM | |
| SCHEMBL13386987 | 0.78 | HCAR2 (0.41) | PSMD14HCAR2MGAMP4HA1P4HTM | |
| SCHEMBL23675229 | 0.78 | BRD4 (0.43) | PSMD14HCAR2MGAMP4HA1P4HTM | |
| SCHEMBL29954886 | 0.77 | CCNT1 (0.39) | PLGPLAUCCNT1CDK9HASPIN | |
| SCHEMBL2549215 | 0.77 | CCNT1 (0.39) | PLGPLAUCCNT1CDK9HASPIN | |
| Hydrochloric Acid SCHEMBL13386995 | 0.76 | HCAR2 (0.40) | PSMD14HCAR2MGAMP4HA1P4HTM | |
| SCHEMBL16044258 | 0.76 | CYP2A6 (0.51) | PLGPLAUCCNT1CDK9HASPIN | |
| SCHEMBL29953488 | 0.76 | CCNT1 (0.38) | PLGPLAUCCNT1CDK9HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |