Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | PARP1 | P09874 | 1/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951290 | 0.97 | KMT2A (0.71) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL5974722 | 0.94 | PARP1 (0.73) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL13480137 | 0.91 | SMN1; SMN2 (0.67) | KMT2AMEN1RAB9AALDH1A1LMNA | |
| SCHEMBL11989152 | 0.89 | KMT2A (0.71) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL11989153 | 0.89 | KMT2A (0.71) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL6150732 | 0.88 | PARP1 (0.74) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL21665206 | 0.87 | MEN1 (0.84) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL2645244 | 0.85 | KMT2A (0.66) | KMT2AMEN1PARP1PARP10RAB9A | |
| SCHEMBL14253775 | 0.84 | KMT2A (0.65) | KMT2AMEN1RAB9AALDH1A1HTT | |
| SCHEMBL29954000 | 0.84 | KMT2A (0.65) | KMT2AMEN1RAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |