Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253775 | 1.00 | KMT2A (0.65) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL28172169 | 0.88 | NPC1 (0.58) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL13480137 | 0.87 | SMN1; SMN2 (0.67) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL14253753 | 0.85 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL5892567 | 0.84 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL5820518 | 0.84 | L3MBTL1 (0.73) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL29951884 | 0.84 | KMT2A (0.76) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL29951290 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL15332168 | 0.84 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2556705 | 0.83 | RAB9A (0.73) | KMT2AMEN1ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |