Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 15/20 | 0.42 |
| ▸ | MEN1 | O00255 | 14/20 | 0.42 |
| ▸ | MAPT | P10636 | 13/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958677 | 0.81 | SMN1; SMN2 (0.96) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL15331670 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1960058 | 0.80 | SMN1; SMN2 (0.73) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL2557965 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1960623 | 0.79 | SMN1; SMN2 (0.71) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL20206188 | 0.73 | POLB (0.63) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1959071 | 0.72 | POLB (0.61) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL2559210 | 0.71 | ALDH1A1 (0.64) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL27959970 | 0.71 | ALDH1A1 (0.47) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL24713215 | 0.69 | ALDH1A1 (0.62) | SMN1; SMN2POLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |