SCHEMBL29951973

SCHEMBL29951973

O=Cc1cccc(OC2CC2)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
TLR2 O60603 1/20 0.42
ERN1 O75460 1/20 0.42
TLR1 Q15399 1/20 0.42
TLR6 Q9Y2C9 1/20 0.42
HRH1 P35367 3/20 0.42
GRIK1 P39086 1/20 0.41
GRIA2 P42262 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPY1R P25929 1/20 0.39
NPY2R P49146 1/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29951166 0.86 ERN1 (0.41) TLR2ERN1TLR1TLR6HRH1
SCHEMBL29953356 0.84 KAT2B (0.50) TLR2ERN1TLR1TLR6HRH1
SCHEMBL11739432 0.80 CA1 (0.69) CA12CA1CA2CA7CA9
SCHEMBL29957098 0.80 CA1 (0.69) CA12CA1CA2CA7CA9
SCHEMBL27983968 0.79 EPHX2 (0.48) CA12CA1CA2CA7CA9
SCHEMBL28427220 0.78 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL21643943 0.78 ALDH1A1 (0.53) TLR2ERN1TLR1TLR6HRH1
SCHEMBL15566857 0.78 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL29955689 0.77 POLB (0.35) HRH1POLBEPHX2
SCHEMBL28421710 0.77 CA12 (0.53) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed