Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953566 | 0.84 | GSK3B (0.43) | GSK3BDYRK1ACDK9ATRRORC | |
| SCHEMBL29954151 | 0.82 | GSK3B (0.44) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL5908666 | 0.82 | GSK3B (0.46) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL28641960 | 0.81 | GSK3B (0.45) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL20049586 | 0.81 | GSK3B (0.45) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL20640507 | 0.80 | KDM4E (0.46) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL20647996 | 0.80 | GSK3B (0.44) | GSK3BDYRK1ASYKCDK9CYP17A1 | |
| SCHEMBL2116624 | 0.80 | GSK3B (0.44) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL31689994 | 0.80 | GSK3B (0.44) | GSK3BDYRK1ASYKCDK9ATR | |
| SCHEMBL29703975 | 0.80 | GSK3B (0.44) | GSK3BDYRK1ASYKCDK9CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |