Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.39 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954151 | 0.90 | GSK3B (0.44) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL18308988 | 0.84 | GSK3B (0.47) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL29951983 | 0.84 | GSK3B (0.43) | GSK3BDYRK1ACDK9ATRMAPKAPK2 | |
| SCHEMBL29957221 | 0.82 | GSK3B (0.44) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL1462818 | 0.82 | GSK3B (0.44) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL20049690 | 0.81 | GSK3B (0.45) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL30380776 | 0.80 | GSK3B (0.44) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL21605283 | 0.78 | GSK3B (0.43) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL30629701 | 0.78 | GSK3B (0.43) | GSK3BDYRK1ACDK9ATRSTK17B | |
| SCHEMBL30381133 | 0.78 | ATR (0.54) | GSK3BDYRK1ACDK9ATRSTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |