SCHEMBL29952033

SCHEMBL29952033

OB(O)c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.86
CA2 P00918 3/20 0.86
ENPP2 Q13822 5/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
MGLL Q99685 2/20 0.45
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HBB P68871 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21352794 1.00 CA1 (0.86) CA1CA2ENPP2CA4CA6
SCHEMBL1153498 1.00 CA1 (0.86) CA1CA2ENPP2CA4CA6
SCHEMBL23150 0.93 CA1 (1.00) CA1CA2ENPP2CA4CA6
SCHEMBL29612616 0.93 CA1 (1.00) CA1CA2ENPP2CA4CA6
SCHEMBL13667343 0.93 CA2 (0.73) CA1CA2ENPP2ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL27818196 0.91 CA1 (0.95) CA1CA2ENPP2CA4CA6
SCHEMBL12025738 0.87 CA1 (0.80) CA1CA2ENPP2MGLL
SCHEMBL205203 0.87 CA2 (0.80) CA1CA2ENPP2CA4CA6
SCHEMBL31354846 0.87 CA2 (0.80) CA1CA2ENPP2CA4CA6
SCHEMBL8781477 0.87 CA1 (0.66) CA1CA2ENPP2ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed