Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630633 | 1.00 | HCAR2 (0.40) | HCAR2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL13813015 | 0.88 | SMN1; SMN2 (0.35) | HCAR2KDM4EALDH1A1CYP3A4TSHR | |
| SCHEMBL68960 | 0.85 | KDM4E (0.47) | HCAR2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL9632777 | 0.84 | HCAR2 (0.40) | HCAR2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL23094464 | 0.78 | NTRK1 (0.39) | HCAR2CYP3A4TDP1SMN1; SMN2KMT2A | |
| SCHEMBL31139857 | 0.78 | NTRK1 (0.39) | HCAR2CYP3A4TDP1SMN1; SMN2KMT2A | |
| SCHEMBL31358930 | 0.77 | KDM4E (0.37) | HCAR2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL29957082 | 0.75 | HCAR2 (0.43) | HCAR2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL3561461 | 0.75 | HCAR2 (0.43) | HCAR2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL8578654 | 0.75 | SMN1; SMN2 (0.45) | HCAR2KDM4EALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |