Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813437 | 0.85 | KMT2A (0.41) | KMT2AMEN1USP2SMN1; SMN2GPR119 | |
| SCHEMBL29953110 | 0.81 | MEN1 (0.40) | KMT2AMEN1USP2SMN1; SMN2GPR119 | |
| SCHEMBL29951277 | 0.79 | HTT (0.36) | KMT2AMEN1USP2SMN1; SMN2GPR119 | |
| SCHEMBL29951583 | 0.74 | NOTUM (0.30) | — | |
| SCHEMBL15252478 | 0.74 | BCHE (0.40) | KMT2AMEN1USP2SMN1; SMN2GPR119 | |
| SCHEMBL5184141 | 0.73 | BCHE (0.47) | KMT2AMEN1GPR119BCHEL3MBTL1 | |
| SCHEMBL23727854 | 0.72 | MEN1 (0.41) | KMT2AMEN1GPR119BCHEESR2 | |
| SCHEMBL1668950 | 0.71 | BCHE (0.36) | KMT2AMEN1GPR119BCHEESR2 | |
| SCHEMBL21541706 | 0.71 | BUB1 (0.37) | KMT2AMEN1GPR119BCHEESR2 | |
| SCHEMBL13559889 | 0.71 | BCHE (0.41) | KMT2AMEN1USP2SMN1; SMN2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |