Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952053 | 0.79 | KMT2A (0.35) | HTTATML3MBTL1MEN1KMT2A | |
| SCHEMBL29953110 | 0.78 | MEN1 (0.40) | HTTATMMEN1KMT2AGPR119 | |
| SCHEMBL29950642 | 0.76 | GAA (0.31) | — | |
| SCHEMBL15252478 | 0.70 | BCHE (0.40) | HTTATML3MBTL1MEN1KMT2A | |
| SCHEMBL28813437 | 0.70 | KMT2A (0.41) | HTTATML3MBTL1MEN1KMT2A | |
| SCHEMBL5184141 | 0.69 | BCHE (0.47) | MAPK1L3MBTL1MEN1KMT2AGPR119 | |
| SCHEMBL1960456 | 0.68 | MEN1 (0.37) | HTTATMMAPK1MEN1KMT2A | |
| SCHEMBL1668950 | 0.68 | BCHE (0.36) | MAPTALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL13559889 | 0.67 | BCHE (0.41) | HTTATMMAPTALDH1A1MAPK1 | |
| SCHEMBL8288797 | 0.67 | BCHE (0.38) | HTTATMMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |