Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950527 | 0.84 | CA1 (0.55) | CA1CA2CA7CA12CA9 | |
| SCHEMBL28345910 | 0.80 | CA12 (0.64) | CA1CA2CA7CA12CA9 | |
| SCHEMBL3229270 | 0.76 | ENPP2 (0.53) | CA1CA2ENPP2MGLLFFAR1 | |
| SCHEMBL26216925 | 0.76 | ENPP2 (0.53) | CA1CA12CA9ENPP2MGLL | |
| SCHEMBL10833567 | 0.74 | CA12 (0.61) | CA1CA2CA7CA12CA9 | |
| SCHEMBL2222368 | 0.73 | ENPP2 (0.62) | CA1CA2CA7CA12CA9 | |
| SCHEMBL22315 | 0.73 | CYP4F2 (0.58) | ENPP2ALOX5 | |
| SCHEMBL3719564 | 0.72 | ENPP2 (0.47) | ENPP2MGLLFFAR1 | |
| SCHEMBL2554457 | 0.71 | ENPP2 (0.55) | CA1CA2ENPP2MGLL | |
| SCHEMBL257658 | 0.71 | ENPP2 (0.55) | ENPP2MGLLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |