Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560755 | 0.90 | HSD17B10 (0.49) | SRCHSD17B10NPSR1ACMSDNFE2L2 | |
| SCHEMBL29952251 | 0.89 | ALDH1A1 (0.43) | SRCHSD17B10NPC1RAB9AKMT2A | |
| SCHEMBL2556757 | 0.88 | SRC (0.50) | SRCHSD17B10NPSR1ACMSDNFE2L2 | |
| SCHEMBL29952197 | 0.86 | ALDH1A1 (0.56) | SRCHSD17B10NPSR1NFE2L2NPC1 | |
| SCHEMBL2556798 | 0.84 | HSD17B10 (0.53) | SRCHSD17B10NPSR1NFE2L2NPC1 | |
| SCHEMBL15329904 | 0.84 | MAPT (0.40) | RAB9AKMT2APOLBMAPTALDH1A1 | |
| SCHEMBL29951271 | 0.83 | PTGDR2 (0.57) | HSD17B10NPSR1NPC1RAB9AKMT2A | |
| SCHEMBL2555240 | 0.83 | SRC (0.56) | SRCHSD17B10NPSR1NFE2L2NPC1 | |
| SCHEMBL20150988 | 0.83 | SRC (0.56) | SRCHSD17B10NPSR1NFE2L2NPC1 | |
| SCHEMBL15330855 | 0.83 | HPGD (0.55) | SRCHSD17B10NPSR1NFE2L2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |