Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700764 | 0.77 | APEX1 (0.55) | APEX1KMT2AKDM4EPTGER4DAO | |
| SCHEMBL5154557 | 0.77 | DAO (0.45) | APEX1KMT2AKDM4EDAOGPR35 | |
| SCHEMBL14620144 | 0.76 | APEX1 (0.53) | APEX1KMT2AKDM4EPTGER4DAO | |
| SCHEMBL26963230 | 0.76 | DAO (0.43) | APEX1KMT2AKDM4EDAOGPR35 | |
| SCHEMBL12995249 | 0.74 | APEX1 (0.52) | APEX1KMT2AKDM4EPTGER4DAO | |
| Hydrochloric Acid SCHEMBL29131528 | 0.74 | DAO (0.42) | APEX1KMT2AKDM4EDAOGPR35 | |
| SCHEMBL4379207 | 0.74 | KDM4E (0.48) | APEX1KMT2AKDM4EDAOGPR35 | |
| SCHEMBL2844554 | 0.74 | APEX1 (0.66) | APEX1KMT2APTGER4TDP1MAPT | |
| SCHEMBL9311435 | 0.72 | KDM4E (0.52) | APEX1KMT2AKDM4EPTGER4DAO | |
| SCHEMBL22638673 | 0.72 | APEX1 (0.46) | APEX1KMT2AKDM4EPTGER4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |