Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953192 | 0.97 | SIGMAR1 (0.49) | SIGMAR1CHRM5CHRM3HPGDCYP3A4 | |
| SCHEMBL29957315 | 0.95 | SIGMAR1 (0.51) | SIGMAR1CHRM5CHRM3HPGDCYP3A4 | |
| SCHEMBL29952105 | 0.95 | SIGMAR1 (0.51) | SIGMAR1CHRM5CHRM3HPGDCYP3A4 | |
| SCHEMBL15329685 | 0.93 | EPHX1 (0.44) | SIGMAR1CHRM5CHRM3HPGDCYP3A4 | |
| SCHEMBL2560386 | 0.90 | SIGMAR1 (0.40) | SIGMAR1CHRM5CHRM3HPGDCYP3A4 | |
| SCHEMBL29957655 | 0.84 | SMN1; SMN2 (0.46) | SIGMAR1CHRM3HPGDLMNAGAA | |
| SCHEMBL15331638 | 0.82 | POLB (0.37) | HPGDLMNAGAAKMT2AALDH1A1 | |
| SCHEMBL2559088 | 0.81 | USP2 (0.46) | LMNAEPHX1KMT2AALDH1A1MAPK1 | |
| SCHEMBL29957813 | 0.80 | SIGMAR1 (0.50) | SIGMAR1CHRM3HPGDLMNAGAA | |
| SCHEMBL15332732 | 0.79 | CHRM5 (0.44) | SIGMAR1CHRM5CHRM3HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |