Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15813516 | 0.84 | TDP1 (0.55) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL15653786 | 0.82 | ERN1 (0.53) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL17429171 | 0.82 | ERN1 (0.53) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL10924787 | 0.80 | IDO1 (0.55) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL15653726 | 0.80 | ERN1 (0.52) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL3080648 | 0.80 | ERN1 (0.52) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL14774597 | 0.78 | ERN1 (0.46) | ERN1TDP1PTPN1VDRLMNA | |
| SCHEMBL5824307 | 0.78 | SRC (0.41) | ERN1PTPN1IDO1SRCALDH1A1 | |
| SCHEMBL19204225 | 0.77 | ERN1 (0.53) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL17428997 | 0.77 | ERN1 (0.48) | ERN1TDP1PTPN1HSD17B10IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |