Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691729 | 0.85 | ERN1 (0.48) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL15652935 | 0.84 | TDP1 (0.55) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL15653786 | 0.82 | ERN1 (0.53) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL17429171 | 0.82 | ERN1 (0.53) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL29952376 | 0.80 | ERN1 (0.52) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL10924787 | 0.80 | IDO1 (0.55) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL15653726 | 0.80 | ERN1 (0.52) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL19204225 | 0.77 | ERN1 (0.53) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL17428997 | 0.77 | ERN1 (0.48) | ERN1TDP1PTPN1HSD17B10IDO1 | |
| SCHEMBL4503640 | 0.76 | SRC (0.40) | ERN1PTPN1IDO1SRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2725005-B1 | METHOD FOR PRODUCING 2-(ARYLOXYMETHYL)BENZALDEHYDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9000225-B2 | Method for producing 2-(aryloxymethyl) benzaldehyde compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20140213825-A1 | METHOD FOR PRODUCING 2-(ARYLOXYMETHYL) BENZALDEHYDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-31 | — | — | US | disclosed |
| EP-2725005-A1 | METHOD FOR PRODUCING 2-(ARYLOXYMETHYL)BENZALDEHYDE COMPOUND | Sumitomo Chemical Company Limited (JP) | 2014-04-30 | — | — | EP | disclosed |
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |
| EP-1807403-A2 | TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-07-18 | — | — | EP | disclosed |
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICHERCHEDI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IRMB) (IT) | 2006-05-11 | — | — | US | disclosed |
| WO-2006046030-A2 | TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | IDO1, ZC3HAV1, IDO2 | ERN1 1733/4885TDP1 3945/4885PTPN1 1153/4885 |
| US-20140213825-A1 | METHOD FOR PRODUCING 2-(ARYLOXYMETHYL) BENZALDEHYDE COMPOUND | AOX1, TYR, PAH | ERN1 2893/4885TDP1 3949/4885PTPN1 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.