Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | EP300 | Q09472 | 2/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647457 | 1.00 | IDO1 (0.46) | IDO1EP300KAT8HDAC3KAT2B | |
| Hydrochloric Acid SCHEMBL17509631 | 0.98 | IDO1 (0.45) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL9099854 | 0.86 | ALDH1A1 (0.59) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL29951906 | 0.86 | ALDH1A1 (0.59) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL982388 | 0.85 | KMT2A (0.61) | IDO1ALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL29786760 | 0.85 | KMT2A (0.61) | IDO1ALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL5749096 | 0.79 | ALDH1A1 (0.43) | IDO1ALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL2459975 | 0.78 | MEN1 (0.46) | IDO1ALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL23105529 | 0.77 | IDO1 (0.46) | IDO1EP300KAT8HDAC3KAT2B | |
| SCHEMBL4555169 | 0.77 | IDO1 (0.46) | IDO1EP300KAT8HDAC3KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |