SCHEMBL29952479

SCHEMBL29952479

O=S(=O)(c1ccccc1B(O)O)N1CCOCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.52
KMT2A Q03164 6/20 0.50
ALDH1A1 P00352 4/20 0.50
POLB P06746 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MEN1 O00255 2/20 0.50
GAA P10253 1/20 0.50
USP2 O75604 1/20 0.49
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPSR1 Q6W5P4 2/20 0.48
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 1/20 0.47
KDM4E B2RXH2 1/20 0.46
CCR8 P51685 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3408339 1.00 NPC1 (0.52) NPC1KMT2AALDH1A1POLBL3MBTL1
SCHEMBL519134 0.85 TSHR (0.67) KMT2AALDH1A1SMN1; SMN2MEN1GAA
SCHEMBL15845803 0.83 TSHR (0.70) KMT2AALDH1A1SMN1; SMN2MEN1GAA
SCHEMBL28250596 0.80 ALDH1A1 (0.54) NPC1KMT2AALDH1A1POLBL3MBTL1
SCHEMBL1911955 0.80 ALDH1A1 (0.63) NPC1KMT2AALDH1A1POLBL3MBTL1
SCHEMBL16599560 0.79 CYP2C9 (0.53) NPC1KMT2AALDH1A1POLBL3MBTL1
SCHEMBL3247291 0.78 CNR1 (0.56) NPC1KMT2APOLBL3MBTL1MEN1
SCHEMBL1988502 0.77 POLB (0.50) NPC1KMT2AALDH1A1POLBL3MBTL1
Hydrochloric Acid SCHEMBL28721405 0.77 ALDH1A1 (0.60) NPC1KMT2AALDH1A1POLBL3MBTL1
SCHEMBL16891569 0.77 NPC1 (0.52) NPC1KMT2AALDH1A1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed