Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 10/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDXK | O00764 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14575607 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL15577964 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL10803937 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL11011837 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL2147331 | 0.74 | NPSR1 (0.39) | KDM4EALDH1A1LMNAERN1TLR2 | |
| SCHEMBL14750234 | 0.73 | IGF1R (0.45) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL22621761 | 0.71 | CYP1A2 (0.34) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL8265770 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL29956056 | 0.71 | CCR1 (0.45) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL3806777 | 0.71 | CCR1 (0.45) | KDM4EALDH1A1HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |