Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16439924 | 0.98 | EPHX2 (0.49) | EPHX2ALDH1A1LMNASLC22A6EPHX1 | |
| SCHEMBL12482731 | 0.91 | EPHX2 (0.56) | EPHX2ALDH1A1LMNASLC22A6EPHX1 | |
| SCHEMBL1288428 | 0.91 | EPHX2 (0.61) | EPHX2ALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL24642929 | 0.91 | EPHX1 (0.53) | EPHX2ALDH1A1LMNASLC22A6EPHX1 | |
| SCHEMBL16439922 | 0.90 | EPHX2 (0.54) | EPHX2ALDH1A1LMNASLC22A6EPHX1 | |
| SCHEMBL2677321 | 0.90 | EPHX2 (0.64) | EPHX2ALDH1A1EPHX1KMT2ACXCR4 | |
| SCHEMBL16440004 | 0.90 | EPHX2 (0.59) | EPHX2ALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL16440007 | 0.88 | EPHX2 (0.62) | EPHX2ALDH1A1EPHX1KMT2ACXCR4 | |
| SCHEMBL21048999 | 0.88 | EPHX2 (0.45) | EPHX2ALDH1A1LMNASLC22A6EPHX1 | |
| SCHEMBL16439978 | 0.88 | EPHX2 (0.62) | EPHX2ALDH1A1EPHX1KMT2ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |