Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928343 | 1.00 | CCR1 (0.39) | CCR1CCR5CCR8PARP1PDPK1 | |
| SCHEMBL29022258 | 0.80 | CCR1 (0.46) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL20036787 | 0.78 | CCR1 (0.68) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL24596414 | 0.73 | CCR1 (0.37) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL26590078 | 0.73 | PARP1 (0.43) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL6242670 | 0.70 | RPS6KA3 (0.41) | CCR1CCR5CCR8PDPK1RPS6KA3 | |
| SCHEMBL27569632 | 0.70 | CCR1 (0.57) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL6698156 | 0.70 | ABCG2 (0.38) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL28751203 | 0.69 | MCHR1 (0.37) | CCR1CCR5CCR8PARP1PDPK1 | |
| SCHEMBL5645444 | 0.68 | MCHR1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |