Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20036787 | 0.89 | CCR1 (0.68) | CCR1CCR5CCR8PARP1PTGER4 | |
| SCHEMBL27569632 | 0.87 | CCR1 (0.57) | CCR1CCR5CCR8PARP1CYP2A6 | |
| SCHEMBL6698156 | 0.83 | ABCG2 (0.38) | CCR1CCR5CCR8PARP1RAB9A | |
| SCHEMBL18984758 | 0.81 | PARP1 (0.35) | CCR1CCR5CCR8PARP1PTGER4 | |
| SCHEMBL29618756 | 0.81 | PARP1 (0.35) | CCR1CCR5CCR8PARP1PTGER4 | |
| SCHEMBL928343 | 0.80 | CCR1 (0.39) | CCR1CCR5CCR8PARP1PTGER4 | |
| SCHEMBL29952549 | 0.80 | CCR1 (0.39) | CCR1CCR5CCR8PARP1PTGER4 | |
| SCHEMBL24596414 | 0.79 | CCR1 (0.37) | CCR1CCR5CCR8PARP1PTGER4 | |
| SCHEMBL29957261 | 0.79 | KDM4E (0.57) | PARP1KDM4E | |
| SCHEMBL28490536 | 0.79 | KDM4E (0.57) | PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118064421-A | Covalent organic framework material immobilized biocatalyst and preparation method and application thereof | 南开大学 | 2024-05-24 | — | — | CN | claimed |
| CN-118064421-A | Covalent organic framework material immobilized biocatalyst and preparation method and application thereof | 南开大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117430766-A | Biological composite material based on covalent organic framework materials (COFs), preparation and application thereof | 南开大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-116284630-A | Reversible redox-catalytic covalent organic framework material, preparation method and application | 中国科学院福建物质结构研究所 | 2023-06-23 | — | — | CN | disclosed |