Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793494 | 1.00 | KDM4E (0.53) | KDM4ENQO1LTA4HALDH1A1TSHR | |
| SCHEMBL29951950 | 0.89 | KDM4E (0.46) | KDM4ENQO1TSHRMEN1KMT2A | |
| SCHEMBL3241115 | 0.89 | KDM4E (0.46) | KDM4ENQO1TSHRMEN1KMT2A | |
| SCHEMBL24994751 | 0.89 | CA1 (0.44) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31119100 | 0.88 | KDM4E (0.43) | KDM4ENQO1LTA4HALDH1A1TSHR | |
| SCHEMBL24994746 | 0.86 | KDM4E (0.44) | KDM4ENQO1LTA4HALDH1A1TSHR | |
| SCHEMBL3786075 | 0.85 | KDM4E (0.49) | KDM4ENQO1LTA4HALDH1A1TSHR | |
| SCHEMBL22208481 | 0.83 | L3MBTL1 (0.44) | KDM4ENQO1TSHRPOLB | |
| SCHEMBL31697241 | 0.83 | L3MBTL1 (0.44) | KDM4ENQO1TSHRPOLB | |
| SCHEMBL29956388 | 0.83 | L3MBTL1 (0.44) | KDM4ENQO1LTA4HALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |