Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | EPX | P11678 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012943 | 0.83 | TDP1 (0.38) | TDP1PDPK1NOS3NOS1NOS2 | |
| SCHEMBL29411195 | 0.78 | TDP1 (0.45) | TDP1ERN1ALDH1A1SRC | |
| SCHEMBL5375502 | 0.78 | NOS3 (0.38) | TDP1PDPK1NOS3NOS1NOS2 | |
| SCHEMBL899188 | 0.78 | TDP1 (0.45) | TDP1ERN1ALDH1A1SRC | |
| SCHEMBL2766838 | 0.75 | NOS3 (0.56) | PDPK1NOS3NOS1NOS2ERN1 | |
| SCHEMBL16333251 | 0.75 | TDP1 (0.42) | TDP1ERN1ALDH1A1SRC | |
| SCHEMBL29956259 | 0.75 | NOS3 (0.56) | PDPK1NOS3NOS1NOS2ERN1 | |
| SCHEMBL15250374 | 0.75 | TDP1 (0.42) | TDP1ERN1ALDH1A1SRC | |
| SCHEMBL31573311 | 0.75 | TDP1 (0.42) | TDP1ERN1ALDH1A1SRC | |
| SCHEMBL29425063 | 0.75 | TDP1 (0.42) | TDP1ERN1ALDH1A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |