Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195760 | 0.81 | LRRK2 (0.47) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL12179269 | 0.81 | LRRK2 (0.52) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL10076882 | 0.78 | KDM4E (0.47) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL16705386 | 0.78 | KDM4E (0.50) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL15743182 | 0.78 | CYP1A2 (0.54) | LRRK2KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL29952663 | 0.78 | CYP1A2 (0.54) | LRRK2KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL21646524 | 0.77 | LRRK2 (0.46) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL9967843 | 0.77 | LRRK2 (0.46) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL13322391 | 0.77 | LRRK2 (0.46) | LRRK2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL13662151 | 0.77 | AOC3 (0.47) | LRRK2KDM4ELMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |