Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743182 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2C9MAPK1POLBLRRK2 | |
| Hydrochloric Acid SCHEMBL29955109 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C9MAPK1POLBLRRK2 | |
| SCHEMBL29953873 | 0.84 | CYP1A2 (0.50) | CYP1A2CYP2C9MAPK1KDM4EKMT2A | |
| SCHEMBL15915410 | 0.84 | CYP1A2 (0.50) | CYP1A2CYP2C9MAPK1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL29957554 | 0.83 | CYP1A2 (0.49) | CYP1A2CYP2C9MAPK1KDM4ELMNA | |
| SCHEMBL1519191 | 0.81 | CHIA (0.52) | CYP1A2 | |
| SCHEMBL2007033 | 0.80 | ALDH1A1 (0.43) | MAPK1PIK3CANPSR1KDM4ELMNA | |
| SCHEMBL18342345 | 0.80 | EPHX2 (0.56) | KDM4E | |
| SCHEMBL29953339 | 0.80 | EPHX2 (0.56) | KDM4E | |
| SCHEMBL3436634 | 0.79 | CYP1A2 (0.56) | CYP1A2CYP2C9MAPK1POLBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |