SCHEMBL29952673

SCHEMBL29952673

OB(O)c1cccc2cc(C(F)F)ccc12

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.38
AKR1B1 P15121 1/20 0.38
KIF11 P52732 1/20 0.38
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
CYP1A2 P05177 2/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
HIF1A Q16665 1/20 0.31
ATM Q13315 1/20 0.30
PLAU P00749 1/20 0.30
MAT2A P31153 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954109 0.86 UGT2B7 (0.38) UGT2B7AKR1B1KIF11AKR1C3AKR1C2
SCHEMBL29951631 0.82 TRPM4 (0.39) UGT2B7AKR1B1KIF11CYP1A2MEN1
SCHEMBL29953232 0.77 CYP1A2 (0.43) CYP1A2
SCHEMBL17728138 0.77 CYP1A2 (0.43) CYP1A2
SCHEMBL29952009 0.76 MAPT (0.37) MEN1KMT2ATSHRATM
SCHEMBL29957465 0.74 TLR8 (0.46) CYP1A2CYP2D6
SCHEMBL4794960 0.74 TLR8 (0.46) CYP1A2CYP2D6
SCHEMBL3186823 0.74 CYP1A2 (0.59) CYP1A2
SCHEMBL29091226 0.73 CYP1A2 (0.41) CYP1A2MEN1KMT2APLAU
SCHEMBL24794301 0.73 CYP2A6 (0.43) CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed