Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954014 | 0.88 | MTNR1A (0.40) | MAPTTSHRMRGPRX4MEN1KMT2A | |
| SCHEMBL29957321 | 0.84 | NPC1 (0.37) | MAPTTSHRMEN1KMT2ANPC1 | |
| SCHEMBL29952201 | 0.81 | KIF11 (0.42) | MRGPRX4KMT2AMTNR1AMTNR1B | |
| SCHEMBL29955414 | 0.80 | CYP1A2 (0.52) | MTNR1AMTNR1B | |
| SCHEMBL4080967 | 0.80 | CYP1A2 (0.52) | MTNR1AMTNR1B | |
| SCHEMBL29952673 | 0.76 | UGT2B7 (0.38) | TSHRMEN1KMT2AATM | |
| SCHEMBL17728138 | 0.73 | CYP1A2 (0.43) | — | |
| SCHEMBL29953232 | 0.73 | CYP1A2 (0.43) | — | |
| SCHEMBL16105620 | 0.72 | ALOX5 (0.59) | MRGPRX4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12646813 | 0.72 | CYP1A2 (0.52) | MAPTTSHRMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |