Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.55 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EDNRB | P24530 | 2/20 | 0.53 |
| ▸ | EDNRA | P25101 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552008 | 0.94 | TP53 (0.60) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL2555312 | 0.91 | TP53 (0.59) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL15330019 | 0.90 | TP53 (0.59) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL2557382 | 0.89 | MAPT (0.68) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL2562869 | 0.87 | KMT2A (0.74) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL2550735 | 0.87 | TP53 (0.61) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL2552975 | 0.86 | KMT2A (0.71) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL29954091 | 0.85 | KDM4E (0.53) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL4885587 | 0.84 | PLA2G10 (0.64) | MAPTTP53PLA2G10PLA2G2AYWHAH | |
| SCHEMBL3720179 | 0.81 | S1PR3 (0.54) | MAPTTP53ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |