Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552008 | 0.89 | TP53 (0.60) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL29952730 | 0.85 | MAPT (0.62) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL2555312 | 0.83 | TP53 (0.59) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL4877551 | 0.83 | ALDH1A1 (0.49) | KDM4EMAPTTP53POLBTHRB | |
| SCHEMBL15330019 | 0.83 | TP53 (0.59) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL2550735 | 0.82 | TP53 (0.61) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL2557382 | 0.82 | MAPT (0.68) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL2552975 | 0.81 | KMT2A (0.71) | MAPTTP53POLBALDH1A1MEN1 | |
| SCHEMBL23865364 | 0.78 | POLB (0.74) | KDM4EPOLBTHRBL3MBTL1ALDH1A1 | |
| SCHEMBL5240000 | 0.77 | KDM4E (0.80) | KDM4EPOLBDYRK1AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |