Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23756878 | 0.76 | HTT (0.55) | — | |
| SCHEMBL1644262 | 0.75 | GRM5 (0.48) | GRM5MAPTPDGFRBPDGFRAAPP | |
| SCHEMBL16598517 | 0.75 | ADK (0.47) | GRM5MAPTPDGFRBPDGFRAAPP | |
| SCHEMBL14276837 | 0.75 | MAP4K4 (0.49) | MAPT | |
| SCHEMBL23283107 | 0.75 | GRM5 (0.49) | GRM5MAPTPDGFRBPDGFRAAPP | |
| SCHEMBL29955261 | 0.75 | MAP4K4 (0.49) | MAPT | |
| SCHEMBL18615838 | 0.73 | MAP4K4 (0.51) | MAPT | |
| SCHEMBL22898349 | 0.72 | APP (0.48) | GRM5ERN1MAPTAPP | |
| SCHEMBL10623779 | 0.70 | APP (0.50) | GRM5ERN1MAPTAPP | |
| SCHEMBL28536669 | 0.69 | FFAR1 (0.47) | GRM5MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |