Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950827 | 1.00 | NOTUM (0.57) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15330773 | 1.00 | NOTUM (0.57) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2558052 | 0.92 | NOTUM (0.68) | NOTUMKDM4EGRM1DRD2DRD4 | |
| SCHEMBL3598593 | 0.86 | AR (0.60) | NOTUM | |
| SCHEMBL4871562 | 0.86 | AR (0.60) | NOTUM | |
| SCHEMBL3607778 | 0.86 | AR (0.60) | NOTUM | |
| SCHEMBL2557970 | 0.83 | FFAR4 (0.53) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2557467 | 0.83 | NOTUM (0.60) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29955392 | 0.83 | NOTUM (0.60) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29956622 | 0.83 | NOTUM (0.60) | NOTUMALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |